基本信息

研究方向

1.肿瘤相关基因的功能与调控

2.细胞信号转导

3.细胞融合与肿瘤转移

科研项目

1.国家自然科学基金面上项目（8212769），2022/01-2025/12，主持

2.国家自然科学基金青年基金项目（8170272），2018/01-2020/12，主持

3.北京市自然科学基金面上项目（5202001），2020/01-2022/12，主持

获奖情况

2022年度北京工业大学校优秀硕士毕业论文指导教师

2018年度北京工业立德树人优秀班主任

代表性研究成果

1．Xin-Ya Wang,Li-Na Zhang*.RNA binding protein SAMD4: current knowledge and future perspectives,Cell & Bioscience,2023, 13(1):21. (JCR 1区)

2. Di-Di Zhang, Xiao-Lin Sun, Zhao-Yuan Liang, Xin-Ya Wang,Li-Na Zhang*. FAM96A and FAM96B function as new tumor suppressor genes in breast cancer through regulation of the Wnt/β-catenin signaling pathway,Life Sciences, 2022,308:120983. (JCR 1区)

3.Li-Na Zhang*, Di-Di Zhang, Lei Yang, Yu-Xuan Gu, Qiu-Ping Zuo, Hao-Yi Wang, Jia Xu, Dian-Xin Liu. Roles of cell fusion between mesenchymal stromal/stem cells and malignant cells in tumor growth and metastasis,TheFEBS Journal,2021,288(5): 1447-1456.（JCR 2区）

4.Xiao-Hui Song#, Xiao-Yan Liao#, Xu-Ying Zheng, Jia-Qian Liu, Zhe-Wei Zhang,Li-Na Zhang*, Yong-Bin Yan*. Human Ccr4 and Caf1 Deadenylases Regulate Proliferation and Tumorigenicity of Human Gastric Cancer Cells via Modulating Cell Cycle Progression,Cancers, 2021, 13(4): 834. (JCR 1区)

5.Li-Na Zhang*,LeiZhao,Xin-Long Yan,Ying-Hui Huang.Loss of G3BP1 suppresses proliferation, migration, and invasion of esophageal cancer cells via Wnt/β-catenin and PI3K/AKT signaling pathways.Journal of Cellular Physiology, 2019, 234(11): 20469-20484.(JCR 1区)

6.Li-Na Zhang*, Ying-Hui Huang, Lei Zhao. Fusion of macrophages promotes breast cancer cell proliferation, migration and invasion through activating epithelial-mesenchymal transition and Wnt/β-catenin signaling pathway.Archives of Biochemistry and Biophysics. 2019, 676: 108137. (JCR 2区)

7.Li-Na Zhang, Chen-Fei Kong, Dan Zhao, Xian-Ling Cong, Shen-Sen Wang, Ling Ma,Ying-Hui Huang*.Fusionwithmesenchymal stem cellsdifferentially affects tumorigenic and metastatic abilities of lung cancer cells.Journal of Cellular Physiology, 2019, 234(4): 3570-3582.(JCR 1区)