徐坤

职称职务:教授 博士生导师

E-mail:kunxu@bjut.edu.cn

通讯地址:北京市朝阳区平乐园100号

基本信息

中国科学技术大学与Rutgers University联合培养博士,2014年获有机化学博士学位,导师汪志勇教授,张绪穆教授。现任北京工业大学教授,博士生导师。主持面上项目等国家自然科学基金三项,以通讯作者在Angewandte Chemie,CCS Chemistry,Science Bulletin,Science China Chemistry,Chemical Science,等期刊上发表研究论文50余篇,其中ESI热点文章2篇,ESI高被引论文7篇。多次入选“全球前2%顶尖科学家榜单”。兼任催化联盟青年工作委员会委员,Chin. J. Org. Chem.青年编委。

研究方向

电化学有机合成,药物分子绿色合成工艺

科研项目

基于LMCT机制的难氧化高键能化学键的电化学氧化活化研究(国家自然科学基金2022-2025)

钴催化的羧酸化合物的脱羧胺化反应研究(国家自然科学基金2017-2019)

电化学诱导的自由基加成反应在含氮稠杂环合成中的应用(国家自然科学基金2016-2018)

近五年部分通讯作者论文

1. Nickel-catalyzed electrochemical Minisci acylation of aromatic N-heterocycles with α-keto acids via ligand-to-metal electron transfer pathway.J. Catal.,2020,381, 38–43.

2. Electroreductive 4-Pyridylation of Electron-deficient Alkenes with Assistance of Ni(acac)2.Org. Lett.,2020,22, 3570–3575.

3. Electrochemical synthesis of selenocyanated imidazo[1,5-a]quinolines under metal catalyst- and chemical oxidant-free conditions.Chin. Chem. Lett.,2020,31, 1576-1579.

4.Recent advances in organic electrosynthesis employing transition metal complexes as electrocatalysts.Sci. Bull.2021,66, 2412-2429.

5. Regioselective C–H Phosphorothiolation of (Hetero)arenes Enabled by the Synergy of Electrooxidation and Ultrasonic Irradiation.Org. Lett.,2021,23, 4214–4218.

6. Access to Deuterated Unnatural α-Amino Acids and Peptides by Photochemical Acyl Radical Addition.Org. Lett.,2021,23, 5299–5304.

7.Electrochemical Arylation of Aldehydes, Ketones, and Alcohols: from Cathodic Reduction to Convergent Paired Electrolysis. Angew. Chem. Int. Ed.,2021,60, 7275-7282.

8. Tandem Strecker/C(sp3)–H amination reactions for the construction of cyanide-functionalized imidazo[1,5-a]pyridines with NH4SCN as a cyanating agent.Org. Chem. Front.,2021,8, 6384-6389.

9. Regioselective intramolecular sp2 C–H amination: direct vs. mediated electrooxidation.Org. Chem. Front.,2021,8, 1581-1586.

10.Recent Applications of Homogeneous Catalysis in Electrochemical Organic Synthesis.CCS Chem.2022,4, 1120-1152.

11. Electrochemical Organoselenium-Catalyzed Intermolecular Hydroazolylation of Alkenes with Low Catalyst Loadings.Org. Lett.2022,24, 5345-5350.

12. Electrophotocatalytic C−H Functionalization of N-Heteroarenes with Unactivated Alkanes under External Oxidant-Free Conditions.ChemSusChem2022,15, e202102360.

13. Electrophotocatalytic Si–H Activation Governed by Polarity-Matching Effects.CCS Chem.2022,4, 1796-1805.

14. The synergism of sequential paired electrosynthesis with halogen bonding activation for the cyclization of organochlorides with olefins.Sci. Chin. Chem.2023,66,540-547.

15. Electrophotoredox/cerium-catalyzed unactivated alkanes activation for the sustainable synthesis of alkylated benzimidazo-fused isoquinolinones.J. Catal.,2023,417, 473–480.

16. Direct alkylation of quinoxalinones with electron-deficient alkenes enabled by a sequential paired electrolysis.Chem. Commun.,2023,59, 12763-12766.

17. Multicomponent Synthesis of 5-Cyano-pyrazolo[1,5-a]pyrimidines Enabled by Aerobic Manganese Catalysis.Adv. Synth. Catal.,2023,365, 871-876.

18. Electrochemical Atom Transfer Radical Addition of Polychloroalkanes to Olefins Promoted by 4,4-Di-tert-butyl Bipyridine.Chin. J. Chem.,2023,41, 1583-1588.

19. Electrochemical Umpolung Enabled Radical–Radical Cross-Coupling Between Electron-Deficient Methylarenes and Aldehydes.CCS Chem.2023,5, 1973-1981.

20. Paired Electrolysis Enabled Trifluoromethylheteroaromatization of Alkenes and Alkyne with Trifluoromethyl Thianthrenium Triflate as a Bifunctional Reagent.Org. Lett.2024,26, 411−415.

21. Visible-Light-Mediated Photocatalyst-Free Hydroacylation of Azodicarboxylic Acid Derivatives with 4-Acyl-1,4-dihydropyridines.Chin. J. Chem.,2024,42, 1230-1236.

22.Electrochemical radical-polar crossover: a radical approach to polar chemistry.Sci. Chin. Chem.2024,67, 450-470.

23. Demystifying the recent photochemical and electrochemical strategies in installing the magic methyl group: a comprehensive overview.Green Chem.2024,26, 8161–8203.

24. The merger of electro-reduction and hydrogen bonding activation for a radical Smiles rearrangement.Chem. Sci.2024,15, 13459–13465.

25. Electrophotochemical ligand-to-metal charge transfer catalysis: an emerging platform for sustainable synthesis.Green Chem.2024,DOI: 10.1039/D5GC00186B.

招生方向

博士:生物医学工程06药物合成与新技术应用;化学

硕士:化学(学硕),生物与医药(专硕)

学校地址:北京市朝阳区平乐园100号
邮政编码:100124

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