基本信息

2013-01至今,北京工业大学,化学与生命科学学院,从事教学科研工作

2007-10 至 2012-03, 牛津大学, 生物医学工程, 博士学位。

2003-09 至 2007-07, 北京理工大学, 特种能源, 学士学位。

研究方向

1.以定制化细胞为主要模型，从细胞骨架、线粒体功能及细胞自噬等多种生物学功能入手，探索肿瘤发展机制。

2.利用分子生物学手段，开发多种用途的基因干预细胞模型。

3.高分辨成像的系统构建，以及基于显微技术的分析系统搭建。

代表性研究成果

1、Hua Huang; Ruining Pan; Yue Zhao; Huan Li; Huiyu Zhu; Sijia Wang; Aamir Ali Khan; Juan Wang;Xinhui Liu*; L3MBTL2-mediated CGA transcriptional suppression promotes pancreatic cancer progression through modulating autophagy, iScience, 2022, 25(5): 104249 .

2、Huang H, Li H, Pan R, Wang S, Khan AA, Zhao Y, Zhu H,Liu X*; Ribosome 18S m6A methyltransferase METTL5 promotes pancreatic cancer progression by modulating cMyc translation. Int J Oncol. 2022 Jan;60(1):9.

3、Khan AA, Huang H, Zhao Y, Li H, Pan R, Wang S,Liu X*;WBSCR22 and TRMT112 synergistically suppress cell proliferation, invasion and tumorigenesis in pancreatic cancer via transcriptional regulation of ISG15. Int J Oncol. 2022 Mar;60(3):24.

4、Hua Huang, Ruining Pan, Sijia Wang, Yifei Guan, Yue Zhao,Xinhui Liu*;Current and potential roles of RNA modification-mediated autophagy dysregulation in cancer, Archives of Biochemistry and Biophysics,2023,736,109542,

5、Huang H, Li H, Zhao T, Khan AA, Pan R, Wang S, Wang S,Liu X*;TSPAN1-elevated FAM110A promotes pancreatic cancer progression by transcriptionally regulating HIST1H2BK. J Cancer. 2022 Jan 1;13(3):906-917.

6、Jing Ren, Jinghan Chi, Baishi Wang, Lingli Guo, Yudi Han, Xinhui Liu*, Xuetao Pei, Wen Yue, Yan Han;Three-dimensional cultivation of human adipose-derived stem cells with human decellularized adipose tissue matrix scaffold promotes diabetic wound healing,Colloids and Surfaces A: Physicochemical and Engineering Aspects,2022,640,128478.

7、Huang H, Li H, Pan R, Wang S,Liu X*. tRNA modifications and their potential roles in pancreatic cancer. Arch Biochem Biophys. 2021 Dec 15;714:109083.

8、Liu X, Khan A, Li H, Wang S, Chen X, Huang H. Ascorbic Acid in Epigenetic Reprogramming. Curr Stem Cell Res Ther. 2022;17(1):13-25.

9、Khan AA^#,Liu X^#, Yan X, Tahir M, Ali S, Huang H. An overview of genetic mutations and epigenetic signatures in the course of pancreatic cancer progression. Cancer Metastasis Rev. 2021 Mar;40(1):245-272.

10、Wang S^#,Liu X^#, Khan AA, Li H, Tahir M, Yan X, Wang J, Huang H. miR-216a-mediated upregulation of TSPAN1 contributes to pancreatic cancer progression via transcriptional regulation of ITGA2. Am J Cancer Res. 2020 Apr 1;10(4):1115-1129.

联系方式

北京工业大学化学与生命科学学院（生命楼B303）

E-mail：liuxinhui@bjut.edu.cn