三、科研项目
[1]国家自然科学基金青年项目, 基于冠脉微循环阻力代偿的瞬时无波幅比无创数值计算研究, 2023-01-01 至 2025-12-31, 30万元, 在研,主持;
[2]北京市自然科学基金面上项目, 智能化、现场型心肌缺血无创诊断技术研究, 2024-01-01 至 2026-12-31, 20万元, 在研,主持;
[3]技术委托项目,明峰医疗基于流体力学的冠心病临床辅助决策系统, 2024-01-01 至 2024-06-30, 15万元, 结题,主持;
[4]中国博士后科学基金面上项目, 基于血流动力学实时反馈调控的智能化体外反搏治疗策略研究, 2021-09-01 至 2023-02-28, 8万元, 结题,主持;
[5]北京市博士后工作经费资助项目, 基于可解释深度学习的冠状动脉精准分割及3D建模方法研究, 2022-01-01 至 2023-12-31, 5.5万元, 结题,主持;
[6]国家重点研发计划,基于流体动力学与数据融合的缺血性心脑疾病计算模拟和临床验证,2021-12-01至2026-11-30,1400万元,在研,参与;
[7]国家重点研发计划, 基于体外反搏技术平台的循环系统智能化康复辅具研发, 2020YFC2004400, 2020-07-01 至 2023-06-30, 521万元, 结题, 参与;
[8]国家自然科学基金重点项目, 冠脉狭窄与心肌缺血定量关系的生物力学研究, 11832003, 2019-01-01 至 2023-12-31, 320万元, 结题, 参与;
[9]北京市自然科学基金-北京市教育委员会科技计划重点项目,基于血流动力学效应优化的体外反搏个性化治疗策略研究,2018-01至2020-12,80万元,结题,参与。
五、代表性研究成果
[1]B Li, G Li*, J Liu, et al. Deep-learning-based real-time individualization for reduce-order haemodynamic model [J]. Computers in Biology and Medicine, 2024, 174:108476. (SCI, 中科院一区)
[2]L Zhang, Y Xu, G Baier, Y Liu,B Li*. Exploring the dynamical transitions on an epileptic hippocampal network model and its modulation strategy based on transcranial magneto-acoustical stimulation [J]. Nonlinear Dynamics, 2024, 112(11):9495–9513. (SCI, JCR一区, top)
[3]H Sun,B Li*, L Zhang, et al. Numerical study of hemodynamic changes in the Circle of Willis after stenosis of the internal carotid artery [J]. Computer Methods and Programs in Biomedicine, 2024, 243, 107881. (SCI, JCR一区, top)
[4]B Li, Y Liu, G Li, et al. A real-time patient-specific treatment strategy for enhanced external counterpulsation [J]. International Journal for Numerical Methods in Biomedical Engineering, 2024, e3808. (SCI, JCR二区)
[5]B Li, Y Liu, J Liu, et al. Cerebral multi-autoregulation model based enhanced external counterpulsation treatment planning for cerebral ischemic stroke [J]. Journal of Cerebral Blood Flow & Metabolism, 2023, 43(10): 1764-1778. (SCI, JCR一区, top)
[6]GF Li, DD Zhong,B Li*, et al. Sleep Deficits Inter-Link Lower Basal Forebrain-Posterior Cingulate Connectivity and Perceived Stress and Anxiety Bidirectionally in Young Men [J]. International Journal of Neuropsychopharmacology, 2023, 26(12): 879-889. (SCI, JCR一区)
[7]M Chen,B Li*, Y Liu, et al. Treatment strategy of different enhanced external counterpulsation frequencies for coronary heart disease and cerebral ischemic stroke a hemodynamic numerical simulation study [J]. Computer Methods and Programs in Biomedicine, 2023, 239:107640. (SCI, JCR一区, top)
[8]B Li#, T Liu#, J Liu, et al. Reliability of using generic flow conditions to quantify aneurysmal haemodynamics: A comparison against simulations incorporating boundary conditions measured in vivo [J]. Computer Methods and Programs in Biomedicine, 2022, 225: 107034. (SCI, JCR一区, top)
[9]K Xu,B Li*, J Liu, et al. Model-based evaluation of local hemodynamic effects of enhanced external counterpulsation [J]. Computer Methods and Programs in Biomedicine, 2022, 214:106540.(SCI, JCR一区, top)
[10]H Sun, J Liu, Y Feng, X Xi, K Xu, L Zhang, J Liu,B Li*, Y Liu*. Deep learning-based prediction of coronary artery stenosis resistance [J]. American Journal of Physiology-Heart and Circulatory Physiology, 2022, 323(6): H1194-1205. (SCI, JCR一区, top)
[11]X Xi, J Liu, H Sun, K Xu, X Wang, L Zhang, T Du, J Liu,B Li*. Accurate calculation of FFR based on a physics-driven fluid–structure interaction model [J]. Frontiers in Physiology, 2022, 13:861446. (SCI, JCR二区)
[12]B Li, B Mao, Y Feng, et al. The hemodynamic mechanism of FFR-Guided coronary artery bypass grafting [J]. Frontiers in Physiology, 2021, 12:503687. (SCI, JCR一区)
[13]B Li, K Xu, J Liu, et al. A numerical model for simulating the hemodynamic effects of enhanced external counterpulsation on coronary arteries [J]. Frontiers in Physiology, 2021, 12:656224. (SCI, JCR一区)
[14]B Li#, H Wang#, G Li, et al. A patient-specific modelling method of blood circulatory system for the numerical simulation of enhanced external counterpulsation [J]. Journal of Biomechanics, 2020, 111:110002. (SCI, JCR三区)
[15]B Li, W Wang, B Mao, et al. Long-term hemodynamic mechanism of enhanced external counterpulsation in the treatment of coronary heart disease: a geometric multiscale simulation [J]. Medical and Biological Engineering and Computing, 2019, 57(11):2417-2433. (SCI, JCR二区)
[16]B Li, W Wang, B Mao, et al. A method to personalize the lumped parameter model of coronary artery [J]. International Journal of Computational Methods, 2019, 16(3):1842004. (SCI, JCR二区)
[17]B Li, W Wang, B Mao, et al. Hemodynamic effects of enhanced external counterpulsation on cerebral arteries: A multiscale study [J]. BioMedical Engineering OnLine, 2019, 18(1):91. (SCI, JCR三区)
[18]刘有军, 王文馨,李鲍, 杜建军. 生物力学建模仿真与应用, 血流动力学几何多尺度数值模拟. 上海交通大学出版社, 2017, 12. (参编)