莫善雁

职称职务:讲师,学术、专业硕士生导师

E-mail:mo@bjut.edu.cn

通讯地址:北京市朝阳区平乐园100号北京工业大学

基本信息

教育背景

(1) 2006-09至2010-06,北京化工大学,应用化学,学士

(2) 2010-09至2015-06,北京化工大学,化学,博士

科研工作经历

(1) 2015-12至2017-01,浙江大学新和成股份有限公司工作站,产品研发

(2) 2017-04至2019-06,北京大学工学院,博士后

研究方向

1.荧光探针的合成与应用

2. EGFR靶向药物设计

科研成果

1. Liming Hu, Yifan Lin, Peng Wang, Hongsheng Zhang, Minyao Liu,Shanyan Mo.A rhodamine derivative probe for highly selective detection of Cu(II), Front. Biosci. (Landmark Ed) 2022 , 27(1), 028.

2. Tianchu Gu,Shanyan Mo,Yingqi Mu, Xin Huang, Liming Hu. Detection of endogenous hydrogen peroxide in living cells with para-nitrophenyl oxoacetyl rhodamine as turn-on mitochondria-targeted fluorescent probe. Sensors and Actuators B: Chemical. 2020, 309, 127731

3.Shanyan Mo, Xiaoting Zhang, Sadaf Hameed, Yiming Zhou, Zhifei Dai. Glutathione-responsive disassembly of disulfide dicyanine for tumor imaging with reduction in background signal intensity. Theranostics, 2020, 10(5), 2130.

4. Chuang Gao#, Xiaolong Liang#,Shanyan Mo#, Nisi Zhang, Desheng Sun, Zhifei Dai. Near-Infrared Cyanine Loaded Liposome-Like Nanocapsules of Camptothecin-Floxuridine Conjugate for Enhanced Chemophotothermal Combination Cancer therapy. ACS Appl. Mater. Interfaces 2018, 10, 3219-3228.

5.Shanyan Mo, Chuangchuang Xu, Jiaxi Xu. Expeditious and Convenient Synthesis of Polycyclic Difluoroboron Complexes of 2-Oxoindoline-3-carboxamides by Tandem Reaction. Adv. Synth. Catal. 2016, 358, 1767–1777.

6.Shanyan Mo, Jiaxi Xu. Chemospecific Intramolecular Buchner Reaction Catalyzed by Copper(II) Acetylacetonate. ChemCatChem 2014, 6, 1679–1683.

7.Shanyan Mo, Xinhao Li, Jiaxi Xu. In Situ Generated Iodonium Ylides as Safe Carbene Precursors for the Chemoslective Intramolecular Buchner Reaction. J. Org. Chem. 2014, 79,

8.Shanyan Mo, Peipei Huang, Jiaxi Xu. Cascade Nitrosation and Addition-Elimination of Nitroacetanilides for the Highly Efficient Synthesis of 1,4,2,5-Dioxadiazine Derivatives. Org. Biomol. Chem. 2014, 12, 4192–4200.

9.Shanyan Mo, Zhanhui Yang, Jiaxi Xu. Aqueous Copper Nitrate Catalyzed Synthesis of 3-Alkylideneoxindoles from α-Diazo-β-ketoanilides. Eur. J. Org. Chem., 2014, 3923–3929.

10.Shanyan Mo.N-Cyano-N-phenyl-p-toluenesulfonamide. Synlett 2014, 25, 1337–1338.

11.Shanyan Mo, Jiaxi Xu. Mechanistic Investigation of the Ring Opening in the Staudinger Cycloaddition Involving Ketenes with Electron-Withdrawing Substituents. Helv. Chim. Acta, 2012, 95, 1079-1086.

12.Shanyan Mo, Jiaxi Xu. Chemospecific synthesis of 2-acetoxyindole-3-carbonitriles catalyzed by Cu(acac)2. Russ. Chem. Bull. 2016, 65, 1773.

13. Yuanzhuo Li, Ke-Qing Zhao, Mark R. J. Elsegood, Timothy J. Prior, Xinsen Sun,Shanyan Mo, Carl Redshaw. Organoaluminium complexes of ortho-, meta-, para-anisidines: Synthesis, structural studies and ROP of ε-caprolactone (and rac-lactide). Catal. Sci. Technol. 2014, 4, 3025–3031.

14. [专利]许家喜,莫善雁.一种3-(羟基亚烷基)吲哚酮的制备方法, CN 201410121521.2

15. [专利]许家喜,莫善雁. 1,4,2,5-二噁二嗪衍生物及其一种简便制备方法, CN 201410091682.1

16. [专利]戴志飞,莫善雁,梁晓龙.三磺基靶向酞菁及其制备方法与用途,中国发明专利,CN 201710974891.4...

在研科研项目

1. 2022,北京市教委一般项目,超低荧光背景近红外双菁染料的肿瘤荧光成像,主持

学校地址:北京市朝阳区平乐园100号
邮政编码:100124

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