曾程初  

曾程初.jpg

曾程初博士,北京工业大学教授,博士生导师,全国有机电化学与工业联合会副理事长。目前主要研究方向为功能有机分子的绿色电化学合成方法、技术及工业化应用。已先后主持国家重点研发计划课题、国家自然科学基金(No.20402001, No. 20772010,21272021, 21472011),北京市自然科学基金(No.2062003,7112008)以及北京市科技新星计划(No. 2005B10)等研究项目。已在Chem. Rev. Org. Lett., Angew. Chem., Chem. Commun., J. Org. Chem.,Eur. J. Org. Chem., Electrochim. Acta 等国内外有机化学和电化学刊物上共发表SCI论文近百篇。

一、个人情况简介:、

1995/09-1998/07,华中师范大学有机合成研究所攻读硕士学位(有机合成专业)。

1998/09-2001/07中国科学院化学研究所攻读博士学位(有机合成专业),获理学博士学位。

2001/10-2003/04,以色列Ben-Gurion大学,博士后。

2003/09—现在,北京工业大学生命学院,教师,副研究员,硕士导师,教授,博士生导师。

2011/04-2011/08美国加州大学圣塔-芭芭拉分校(UCSB)化学与生物化学系,访问学者。

二、主要研究方向:

有机电化学合成:将有机化学、电化学和绿色化学的概念、方法和技术引入到化学键的电化学活化及其原位转化中,研究功能有机分子的绿色电化学合成的机理与工业化应用。主要体现在:

1.有机电催化剂的创制及其在合成中的应用

2.电化学原位产生的碱诱导的反应及其在有机合成中的应用

3.基于卤素离子为电催化剂的化学键的电化学形成与断裂的机制及工业化应用

4.高附加值精细化学品的电化学制备

三、主持的研究课题:

1.国家重点研发计划课题:基于卤素离子的间接电催化氧化合成关键技术及其示范(2017/07-2020/12)

2. 国家重点研发计划子课题:食用香料香精和配料绿色制造关键技术研究(2016/7-2020/12

3. 企业委托项目:香料的电化学合成研究(2015/01-2019/12

4. 国家自然科学基金(21871019):碳自由基的电化学可控形成及其在Minisci 反应中的应用(2018/01-2022/12

5. 国家自然科学基金(21472011):卤素离子为媒介的电化学氧化偶联形成新的C-C键或C-N键的研究(2015/01-2018/12

6. 国家自然科学基金(21272021):新型三芳基咪唑类有机电催化剂的创制及其电氧化活化C-H键和C-C键研究(2013/01-2016/12

7. 国家自然科学基金(20772010)水相中邻苯醌衍生物的电化学合成与原位转化。(2008/01-2010/12

8. 国家自然科学基金(20402001)磺酰胺苯乙烯基喹啉新型HIV整合酶抑制剂的设计、合成及其构效关系研究( 2005/01-2007/12

四、研究论文(近三年)

1.   Hang Ding, Kun Xu,* and Cheng-Chu Zeng* Nickel-catalyzed electrochemical Minisci acylation of aromatic N-heterocycles with α-keto acids via ligand-to-metal electron transfer pathway, J. Catal., 2020, 381, 38-43.

2. Yong Li, Cao-Cao Sun, Cheng-Chu Zeng* Electrocatalytic synthesis of thiazoles mediated by bromide/tetrachlorohydroquinone dual redox catalysts, J. Electroanal. Chem., 2020, 861, 113941.

3. Liang, S.; Zeng, C.-C.* Organic electrochemistry: Anodic construction of heterocyclic structures, Curr. Opin. Electrochem., 2020, 24, 31-43

4. Zhenxing Zhang, Lei Zhang, Xianhao Zhang, Jianxin Yang, Yunxing Yin, Yangye Jiang, Chengchu Zeng, Gang Lu, Yang Yang, Fanyang Mo, Anodic oxidation triggered divergent 1,2- and 1,4-group transfer reactions of b-hydroxycarboxylic acids enabled by electrochemical regulation, Chem. Sci., 2020, 11, 12021-12028.

5.  Sun, Xue-Jie Yang, Shang-Feng Wang, Zhi-Tong Liang, Sen Tian, Hong-Yu Yang, Shao-Xiang Liu, Yong-Guo Sun, Bao-Guo Zeng, Cheng-Chu, Electrochemically Oxidative Coupling of S-H/S-H for S-S Bond Formation: A Facile Approach to Diacid-disulfides, Chem. Sect., 2020, 5, 4637-4641.

6. Fei Lian, Caocao Sun, Kun Xu and Chengchu Zeng* Electrochemical Dehydrogenative Imidation of N-methyl Substituted Benzylamines with Phthalimides for the Direct Synthesis of Phthalimide-protected gem-Diamines Org. Lett., 2019, 21, 156-159.

7. Cao-Cao Sun, Kun Xu and Cheng-Chu Zeng* Transition metal- and base-free electrochemical aza-Michael addition of aromatic aza-heterocycles or Ts-protected amines to α,β-unsaturated alkenes mediated by NaI ACS sustainable Chem. Eng. 2019, 7, 2255-2261.

8. Cao-Cao Sun, Fei Lian, Kun Xu, Cheng-Chu Zeng,* and Bao-Guo Sun,* Electrochemical Synthesis of Allylamines via a Radical Trapping Sequence Adv. Synth. Catal. 2019, 361, 4041–4047.

9.  Ke-Jing Li, Kun Xu, Yong-Guo Liu, Cheng-Chu Zeng*, and Bao-Guo Sun Electrochemical dehydrogenative cross-coupling of quinoxalin-2(1H)-ones with amines for the synthesis of 3-aminoquinoxalinones Adv. Synth. Catal. 2019, 361, 1033-1041.

10.Ke-Jing Li, Yang-Ye Jiang, Kun Xu, Cheng-Chu Zeng *and Bao-Guo Sun Electrochemically dehydrogenative C–H/P–H cross-coupling: effective synthesis of phosphonated quinoxalin-2(1H)-ones and xanthenes Green. Chem., 2019, 21, 4412-4421.

11. Gui-Yuan Dou, Yang-Ye Jiang, Kun Xu and Cheng-Chu Zeng * Electrochemical Minisci-type trifluoromethylation of electron-deficient heterocycles mediated by bromide ions Org. Chem. Front., 2019, 6, 2392-2397.

12.Xiu-zhi Wang, Chengchu Zeng, Iron-catalyzed Minisci acylation of N-heteroarenes with α-keto acids Tetrahedron, 2019, 75, (10), 1425-1430.

13. Qing-Qing Wang, Yang-Ye Jiang, Cheng-Chu Zeng,*and Bao-Guo Sun*, Electrocatalytic Synthesis of Non-Symmetric Biphenols Mediated byTri(p-bromophenyl)amine: Selective OxidativeCross-Coupling ofDifferent Phenols and Naphthols Chin. J. Chem. 2019, 37, 352—358.

14.Yeerlan Adeli, Kaimeng Huang, Yujie Liang, Yangye Jiang, Jianzhong Liu, Song Song, Cheng-Chu Zeng,* and Ning Jiao*, Electrochemically Oxidative C−C Bond Cleavage of Alkylarenes for Anilines Synthesis ACS Catal. 2019, 9, 2063−2067.

15. T. Golub, Gui-Yuan Dou, Chengchu Zeng, James. Y. Becker, One-Pot Anodic Conversion of Symmetrical Bisamides of Ethylene Diamine to Unsymmetrical gem-Bisamides of Methylene Diamine, Org. Lett., 2019, 21, 7961-7964.

16. Yang-ye Jiang, Gui-yuan Dou, Luo-sha Zhang, Kun Xu, R. Daniel Little, Cheng-chu Zeng* Electrochemical cross-coupling of C(sp2)-H with aryldiazonium salts via a paired electrolysis: an alternative to visible light photoredox-based approach Adv. Synth. Catal. 2019, 361, 5170-5175.

17.  Fei Lian, Kun Xu,* Wei Meng, Haonan Zhang, Zhoumei Tan, and Chengchu Zeng* Electrochemical Nickel-catalyzed Reductive Decarboxylative Coupling of N-hydroxyphthalimide esters with Quinoxalinones, Chem. Commun. 2019, 55, 14685-14688.

18. Yangye Jiang, Kun Xu and Chengchu Zeng* The use of electrochemistry in the synthesis of heterocyclic structures Chem. Rev. 2018, 118, 4485-4540.

19. Mi-Hai Luo, Yang-Ye Jiang, Kun Xu, Yong-Guo Liu, Bao-Guo Sun and Cheng-Chu Zeng* Functionalization of N-arylglycine esters: electrocatalytic access to C–C bonds mediated by n-Bu4NI Beilstein J. Org. Chem. 2018, 14, 499-505.

20.  Meng-Ying Lin, Kun Xu, Yang-Ye Jiang, Yong-Guo Liu, Bao-Guo Sun, and Cheng-Chu Zeng,* Intermolecular Electrochemical C(sp3)-H/N-H Cross-coupling of Xanthenes with N-alkoxyamides: Radical Pathway Mediated by Ferrocene as a Redox Catalyst Adv. Synth. Catal. 2018, 360, 1665-1672.

21. Yang-Ye Jiang, Gui-Yuan Dou, Kun Xu and Cheng-Chu Zeng* Bromide-catalyzed electrochemical trifluoromethylation/cyclization of N-arylacrylamides with low catalyst loading Org. Chem. Front., 2018, 5, 2578-2582.

22. Sen Liang, Kun Xu, Cheng-Chu Zeng,* Hong-Yu Tian, and Bao-Guo Sun,* Recent Advances in the Electrochemical a-C–H Bond Functionalization of Carbonyl Compounds Adv. Synth. Catal. 2018, 360, 4266-4292.

23. Sen Liang, Cheng-Chu Zeng,* Hong-Yu Tian, Bao-Guo Sun,a,* Xu-Gang Luo, and Fa-zheng Ren Redox Active Sodium Iodide/Recyclable Heterogeneous Solid Acid: An Efficient Dual Catalytic System for Electrochemically Oxidative a-C-H Thiocyanation and Sulfenylation of Ketones Adv. Synth. Catal. 2018, 360, 1444-1452.

24. Sheng Zhang,* Lijun Li, Mengyu Xue, Ruike Zhang, Kun Xu,* and Chengchu Zeng* Electrochemical Formation of N-Acyloxy Amidyl Radicals and Their Application: Regioselective Intramolecular Amination of sp2 and sp3 C−H Bonds Org. Lett. 2018, 20, 3443-3446.

25. Sheng Zhang,* Lijun Li, Huiqiao Wang, Qian Li, Wenmin Liu, Kun Xu,*and Chengchu Zeng* Scalable Electrochemical Dehydrogenative Lactonization of C(sp2/sp3)−H Bonds Org. Lett. 2018, 20, 252-255.

五、联系方式

曾程初博士

北京工业大学环境与生命学部

北京市朝阳区平乐园100

Tel.: 010-67396211

E-mail: zengcc@bjut.edu.cn

 










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